Smart Innovation

Antimicrobial resistance (AMR)

AMR develops when bacteria, fungi or viruses are exposed to antibiotics, antifungals or antivirals. As a result, the antimicrobials become ineffective and infections may persist. In addition, medical interventions including surgery, chemotherapy and stem cell therapy may become impossible. 
AMR is considered the biggest global threat of Health and Food Safety.

AMR Insights

For Researchers and Entrepreneurs who wish to investigate, develop and commercialize novel vaccines, diagnostics and antimicrobials to prevent Antimicrobial resistance, AMR Insights offers selected, global information and data, specific education and extensive networking and partnering opportunities. 

AMR Insights is for:

  • Researchers at Universities and University Medical Centers
  • Researchers at Research Institutes
  • R&D professionals in Pharma, Biopharma and Diagnostics companies
  • Entrepreneurs in start-up’s and spin off companies
  • Innovators, Venture Capitalists.

Latest Topics

  •   18 March 2024

    Accurate and rapid antibiotic susceptibility testing using a machine learning-assisted nanomotion technology platform

    Antimicrobial resistance (AMR) is a major public health threat, reducing treatment options. A rapid growth-independent phenotypic AST using nanomotion technology measures bacterial vibrations. Machine learning techniques analyze a large dataset, achieving 90.5-100% accuracy. Independent testing on 223 strains predicts susceptibility and resistance with accuracies between 89.5% and 98.9%, demonstrating potential for future bacterial phenotype delineation.

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  •   16 March 2024

    In vivo evolution of antimicrobial resistance in a biofilm model of Pseudomonas aeruginosa lung infection

    The study investigates the development of antimicrobial resistance (AMR) in a mouse model of Pseudomonas aeruginosa biofilm lung infection. The mice were exposed to ciprofloxacin and showed a rapid development of AMR. Genetic analysis revealed mutations in nfxB, efflux pumps, and parS contributing to CIP resistance. The CIP-treated mice also exhibited an elevated inflammatory response, […]

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  •   15 March 2024

    Isolation and characterization of lytic bacteriophages from various sources in Addis Ababa against antimicrobial-resistant diarrheagenic Escherichia coli strains and evaluation of their therapeutic potential

    This study aimed to isolate and characterize lytic bacteriophages from various sources in Addis Ababa, test them against antimicrobial-resistant diarrheagenic E. coli strains, and evaluate their therapeutic potential under in vitro conditions. A total of 17 phages were recovered from 84 tested plates, with 7 potent phages selected based on host range test, growth characteristics, […]

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