Does the “Holism theory” Explain the Increase in Antimicrobial Efficacy and the Lack of Acquired or Innate Resistance to 5th Generation Silane Quaternary Compounds?

  07 February 2020

There are essentially two main groups of quaternary ammonium compounds (Quats), those that have a silane attached, and those that do not. Whilst their mode of action (MOA) is essentially the same, the spectrum of species kill and the level of persistence are very different for each variation. The silane versions of the Quats (SiQuats) will bond to surfaces and skin and become, in some cases, almost impossible to remove without wearing away the surface to which they are bonded. The resultant effect, therefore, is an antimicrobial compound that remains in place killing microbes for days months or years. 

 

Author(s): Andrew Kemp, Shalom Hirschman, Vanessa Hodgkinson
Clean Environment   Healthy Patients   Smart Innovations  
Back

OUR UNDERWRITERS

Unrestricted financial support by:

LifeArc

Antimicrobial Resistance Fighter Coalition

Bangalore Bioinnovation Centre

INTERNATIONAL FEDERATION PHARMACEUTICAL MANUFACTURERS & ASSOCIATIONS





Ambassador Network

Join the AMR Insights Ambassador Network today!

Connect to over 650 AMR professionals and students in 65 countries!

Register

What is going on with AMR?
Stay tuned with remarkable global AMR news and developments!

Keep me informed