Plastic-mediated transformation: A new route to navigate plasmid-borne antibiotic resistance genes

Plastic polymers in aquatic ecosystems are increasing pollution and attracting bacteria for colonization and horizontal gene transfer (HGT). A study tested bacteria’s ability to acquire plasmid DNA under various treatments, including soil, CaCl2 salt solution, and plastic debris. Results showed plastic fragments were efficient in increasing bacterial competence for DNA uptake. The study suggests that simultaneous incubation of microorganisms, plasmids, and plastic fragments enhances bacterial ability to uptake plasmids and express genes for survival under stress conditions.