Impact of screening on the prevalence and incidence of Mycoplasma genitalium and its macrolide resistance in men who have sex with men living in Australia: A mathematical model

  05 March 2021

Mycoplasma genitalium (MG) causes a sexually transmitted infection (STI) with a rising rate of antimicrobial resistance. Currently, guidelines do not recommend screening asymptomatic men who have sex with men (MSM). We developed a mathematical model of MG transmission to examine the impact of various screening strategies on the incidence and prevalence of MG among MSM attending a sexual health clinic.

When evaluating the simultaneous impact of treatment effectiveness and screening coverage, we found that offering screening to more MSM may reduce the overall prevalence but leads to a higher proportion of macrolide-resistant MG, particularly when using treatment regimens with lower effectiveness.

Further reading: E-Clinical Medicine
Author(s): Jason J. Ong Luanqi Ruan Aaron G. Lim Catriona S. Bradshaw David Taylor-Robinson Magnus Unemo Patrick J. Horner Peter Vickerman Lei Zhang
Effective Surveillance   Healthy Patients  
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