Understanding antimicrobial resistance (AMR) mechanisms and advancements in AMR diagnostics
Antimicrobial resistance (AMR) is a global health catastrophe caused by antibiotic overuse and abuse, leading to the evolution of resistant microorganisms. Mechanisms such as enzymatic breakdown, target site modification, efflux pump overexpression, and biofilm formation complicate treatment options and increase mortality rates. Advanced AMR diagnostics, such as biosensors, CRISPR technologies, mass spectrometry, automated systems, and flow cytometry, are transforming the fight against AMR.
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