Serotype Profile of Nasopharyngeal Isolates of Streptococcus pneumoniae Obtained from Children in Burkina Faso before and after Mass Administration of Azithromycin

  10 June 2020

Mass drug administration (MDA) with azithromycin (AZ) has been used successfully to control trachoma. However, several studies have shown that MDA with AZ has led to the emergence of resistance to AZ in  The emergence of resistance to AZ has also been observed when this antibiotic was combined with the antimalarials used for seasonal malaria chemoprevention (SMC). The development of antibiotic resistance, including resistance to AZ, is sometimes associated with the emergence of a bacterial clone that belongs to a specific serotype. We hypothesize that the increase in resistance of  observed after 3 years of SMC with AZ might be associated with a change in the distribution of pneumococcal serotypes.

Author(s): Soumeya Hema-Ouangraoua, Issaka Zongo, Nongodo Firmin Kabore, Nikiema Frédéric, Serge Yerbanga, Halidou Tinto, Yves Daniel Compaore, Irene Kuepfer, Daniel Chandrahoman, Brian Greenwood and Jean Bosco Ouedraogo
Effective Surveillance   Healthy Patients  
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