Prevalence and distribution of antimicrobial resistance determinants of Escherichia coli isolates obtained from meat in South Africa

  28 May 2020

This study revealed a high burden of resistance against important antimicrobials such as streptomycin, neomycin, ceftriaxone, chloramphenicol, and tetracycline, including imipenem and meropenem. Genes encoding cephalosporin resistance are commonly situated on self-transmissible plasmids which may be promiscuous and capable of disseminating into a broad range of microbiota. Furthermore, the resistance of Ecoli isolates to antibiotics of choice in human therapy such as aminoglycoside, chloramphenicol, carbapenem, and cephalosporin pose a grave danger for success in human chemotherapy. Resistance in nitrofurantoin, a drug not commonly in use in South Africa, suggests that factors other than selective pressure must have an impact on the emergence of resistant Ecoli.

Further reading: Plos One
Author(s): Ishmael Festus Jaja, James Oguttu, Chinwe-Juliana Iwu Jaja, Ezekiel Green
Healthy Animals   Secure Foods  


Unrestricted financial support by:


Antimicrobial Resistance Fighter Coalition

Bangalore Bioinnovation Centre


EADA 2023

Emerging Antimicrobials and Diagnostics in AMR 2023

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