Phase 1 safety trial of a natural product cocktail with antibacterial activity in human volunteers

  19 November 2022

New antibiotics are urgently needed to reduce the health burden of antibiotic-resistant bacterial infection. Natural products (NPs) derived from plants and animals are a current focus of research seeking to discover new antibacterial molecules with clinical potential. A cocktail of NPs based on a medieval remedy for eye infection eliminated biofilms of several highly antibiotic-resistant bacterial species in laboratory studies, and had a promising safety profile in vitro and in a mouse model.

Further reading: Nature Scientific Reports
Author(s): Julie Bruce, Blessing Oyedemi, Nick Parsons & Freya Harrison
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