Peptide weakens superbugs to make old antibiotics effective again

  01 May 2020

For the new study, researchers from Örebro and Linköping Universities identified an antibacterial peptide and how it could be put to work. The peptide is known as plantaricin, and is derived from a probiotic bacteria that’s often used as a preservative in foods like pickles and sauerkraut.

The team pitted plantaricin against methicillin-resistant Staphylococcus aureus (MRSA). This superbug, often called “golden Staph,” is a common pest in hospitals that causes infections in wounds or implants that can turn dangerous.

In tests, plantaricin was found to dissolve the bacterial membrane, allowing the drugs to get in and kill the superbugs much more easily. That would give existing, tired drugs a new lease on life, expanding our arsenal and delaying the advance of the superbug. Plus, required dosages are much lower.

Further reading: New Atlas
Author(s): Michael Irving
Smart Innovations  
Back


Display your AMR technology / product:

Global AMR Technologies Database

  • Preventive – Diagnostic – Antimicrobial technologies
  • Academia – Research Institutes – Start ups – SMEs – Multinationals
  • Early research <-> near market
  • Global reach for funding / co-development / licensing
Display your technology and make use of the Continuous AMR Partnering Initiative >>
What is going on with AMR?
Stay tuned with remarkable global AMR news and developments!