Metapopulation ecology links antibiotic resistance, consumption, and patient transfers in a network of hospital wards
Antimicrobial resistance (AMR) is a global threat. A better understanding of how antibiotic use and between-ward patient transfers (or connectivity) impact population-level AMR in hospital networks can help optimize antibiotic stewardship and infection control strategies. Here, we used a metapopulation framework to explain variations in the incidence of infections caused by 7 major bacterial species and their drug-resistant variants in a network of 357 hospital wards. We found that ward-level antibiotic consumption volume had a stronger influence on the incidence of the more resistant pathogens, while connectivity had the most influence on hospital-endemic species and carbapenem-resistant pathogens.
International Matchmaking Symposium 18 November 2020
Emerging Antimicrobials & Diagnostics in AMR 2020
4th AMR Insights International Symposium to provide an international online podium for emerging preventives, new antimicrobial strategies, microbial diagnostics and related (platform) technologies.