Mathematical Modelling to Study the Horizontal Transfer of Antimicrobial Resistance Genes in Bacteria: Current State of the Field and Recommendations

The findings highlight the existence of an important research gap on the dynamics of transformation and transduction, and the overall public health implications of horizontal transfer of AMR genes. To further develop this field and improve our ability to control AMR, it is essential that we clarify the structural complexity required to study the dynamics of horizontal gene transfer, which will require cooperation between microbiologists and modellers.