Identification of clinically relevant multi-drug resistant ESKAPEE isolates from hospital wastewater surveillance in Thailand
This study in a Thai tertiary hospital compared wastewater surveillance with clinical isolates to assess its value for AMR monitoring. From hospital wastewater, researchers isolated 2,735 AMR bacteria (including 1,550 ESKAPEE pathogens), with high levels of multidrug resistance—most notably in Klebsiella pneumoniae (85%) and E. coli (98%). Drug-resistance patterns in wastewater overlapped strongly with clinical isolates, and whole-genome sequencing confirmed close genetic relatedness, including multiple wastewater isolates identical to clinical strains.
Conclusion: Untreated hospital wastewater can serve as a powerful, clinically relevant surveillance tool for tracking multidrug-resistant ESKAPEE pathogens
OUR UNDERWRITERS
Unrestricted financial support by:
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Antimicrobial Resistance Fighter Coalition |
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Bangalore Bioinnovation Centre |
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INTERNATIONAL FEDERATION PHARMACEUTICAL MANUFACTURERS & ASSOCIATIONS |
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BD |
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