Framework of actions to contain carbapenemase-producing Enterobacterales
This framework focuses on carbapenemase-producing Enterobacterales
(CPE) because these organisms spread rapidly in healthcare settings and
leading to poor clinical outcomes because of limited therapeutic options.
The increased incidence of CPE has significant cost and operational implications for healthcare providers.
Unless action is taken, learning from experiences elsewhere in the world,
rapid spread of CPE will pose an ever-increasing threat to public health and
medical treatment pathways in the UK.
The framework sets out a range of measures, that if implemented well, will
help health and social care providers minimise the impact of CPE. These
- active patient admission screening of risk groups
- rapid detection of patients colonised or infected with CPE to enable
spread, with appropriate surveillance systems to capture this
- prompt recognition of outbreaks and clusters to enable effective
- consistent implementation of infection prevention and control
- minimisation of CPE reservoirs by effective environmental cleaning
- antimicrobial stewardship programmes to minimise inappropriate use
of broad spectrum antibiotics, including carbapenems
- optimised laboratory methods to detect carbapenemase producing
- organisational ownership to support the implementation of this
This document recognises that the evidence base for some
recommendations is limited and that local risk assessment is important for
building a local CPE policy that can be implemented based on the
Display your AMR Technology, Product and Service
Suppliers and Users of Technologies, Products and Services benefit from CAPI.
CAPI (Continuous AMR Partnering Initiative) unites Suppliers and Users worldwide with the aim to add to the curbing of AMR.