Evidence for selection of multi-resistant E. coli by hospital effluent

  20 February 2021

There is a risk that residues of antibiotics and other antimicrobials in hospital and municipal wastewaters could select for resistant bacteria. Still, direct experimental evidence for selection is lacking. Here, we investigated if effluent from a large Swedish hospital, as well as influent and effluent from the connected municipal wastewater treatment plant (WWTP) select for antibiotic resistant Escherichia coli in three controlled experimental setups. Exposure of sterile-filtered hospital effluent to a planktonic mix of 149 different E. coli wastewater isolates showed a strong selection of multi-resistant strains. 


Further reading: Environment International
Author(s): Nadine Kraupner et al
Clean Environment  


Unrestricted financial support by:

Antimicrobial Resistance Fighter Coalition


JSS University


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