Effectiveness of Single vs Multiple Doses of Prophylactic Intravenous Antibiotics in Implant-Based Breast Reconstruction
Do rates of postoperative surgical site infections after implant-based breast reconstruction improve when using a multiple-dose instead of a single-dose prophylactic antibiotic regimen?
In this randomized clinical trial, there were no differences in rates of postoperative infections among patients managed with single vs multiple doses of prophylactic antibiotics; multiple doses were associated with higher rates of adverse events.
Multiple-dose intravenous antibiotic prophylaxis is not superior to a single-dose regimen in preventing postoperative infection after implant-based breast reconstruction and is not recommended because of the associated higher rates of adverse events.
Join the AMR Insights Ambassador Network today!
Connect to over 550 AMR professionals and students in 60 countries!