Bacterial Antimicrobial Resistance: Data Gaps and Relationships between Human and Animal Resistance

Bacterial antimicrobial resistance (AMR) is a global threat. There is concern to the degree that the agricultural sector contributes to human AMR, given the interconnected nature of humans, animals, and the environment. A global analysis pairing human and livestock AMR through a One Health lens has not been done to date. We aim to identify critical data gaps in this area.

Fluoroquinolones should continue to be monitored extensively due to their high resistance and usage in several countries, and interventions should be pathogen specific. Aminopenicillins, while lesser prioritized in human medicine, should also be monitored extensively given the significant relationship between human and livestock AMR. Integrated AMR surveillance systems can be localized to specific contexts and relevant livestock species, be dynamic to account for changing antimicrobial usage trends, and be sustainable in consistently testing across relevant pathogens, antimicrobials and livestock species.