Antimicrobial resistance among children in Africa: need for paediatric clinical trials
Clinical trials are the gold standard for generating evidence-based knowledge in medicine. A disproportionately small number of clinical trials are conducted in children, a unique population who require age- and development-specific treatments. The rise in prevalence of antimicrobial resistant (AMR) – specifically antibacterial resistant – pediatric infections in both community and hospital settings in Africa has not been matched by increases in access to effective antimicrobial therapy. In many low-resource settings, empirical antimicrobial therapies are no longer effective, and therapeutic options for AMR pathogens are either unaffordable or unavailable locally.
Boosting innovation to curb AMR?
AMR Innovation Mission UK 2021
The AMR Innovation Mission UK 2021 aims to add to the global curbing of AMR by boosting joint early & translational research, R&D, clinical development, validation, registration and commercialisation of vaccines, microbial diagnostics and antimicrobial products.