DOSAGE: Dataset for Optimized Safe Antibiotic Guidelines and Estimates

A 2025 Scientific Data article introduces DOSAGE — the Dataset for Optimized Safe Antibiotic Guidelines and Estimates — designed to improve antibiotic dosing practices and support antimicrobial stewardship. The open dataset compiles structured information from published literature and public sources on antibiotic prescriptions, including drug, dose, indication, patient characteristics, and outcomes. By systematically capturing and validating this data, DOSAGE reveals substantial variation in dosing practices across infections and patient groups, highlighting opportunities to optimise treatment and reduce antimicrobial resistance. The authors demonstrate how the dataset can be used to model dosing strategies, update clinical guidelines, and inform safer, evidence-based prescribing. Although limited by incomplete or uneven data coverage, DOSAGE represents a foundational step toward data-driven antibiotic stewardship and more precise global dosing recommendations.