BIC – bacterial impedance cytometry

A novel, fast, simple, single cell approach to monitor the tiny electrical changes taking place in bacteria in response to antimicrobial agents.

Fast, adaptable, label-free, phenotypic method giving novel insights into bacterial responses.

Technology:
  • Antimicrobial stewardship
  • Microbial diagnostics
  • Antimicrobial compound/strategy
  • Infection prevention
  • Removal antibiotics/bacteria

Microorganisms:
  • Bacteria
  • Viruses
  • Fungi
  • Yeasts
  • Parasites

Application:
  • Human
  • Veterinary
  • Other
  • AgriFood
  • Environmental

Development stage:
  • Research
  • Development
  • Validation
  • Market entry
  • Marketed product

Organization:
  • Government
  • Company
  • Academia
  • Institute
  • NGO

Partnering:
  • Co-develop
  • Joint Venture
  • License
  • Outsource
  • Sell

Funding organisation:
  • GARDP
  • OTHER / NA
  • CARB-X
  • FIND
  • REPAIR

Infectious disease area:
  • UTI
  • STI
  • BSI
  • RTI
  • GII
  • SSTI
  • CNSI
  • IAI
  • SSI

Geographic origin:
  • Eurasia
  • North America
  • South America
  • Africa
  • Oceania


Companies, academics, charities, SMEs interested in an open innovation approach to antimicrobial discovery and evaluation.

UKHSA is an executive agency of the Department of Health. UKHSA Porton specialises in R&D incl. new antimicrobial therapies, vaccines & diagnostics. The AD3 (Antimicrobial Discovery, Development and Diagnostics) Group aims to develop new interventions for antimicrobial resistance (AMR) and healthcare associated infections (HCAI). The team uses a variety of approaches to develop real life solutions to practical problems and takes an interdisciplinary approach, working with a variety of groups in life sciences, chemistry, physical sciences and engineering.

Technology to support early stage evaluation of antimicrobials, including companion diagnostics. Other applications: AST for UTI, MRSA, N. gonorrhoeae; characterisation of bacteriophage infection & host susceptibility; research tool to investigate modes of action, mechanism of resistance etc. As read-out takes 30 seconds, immediate changes can be seen.


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