Significant Regional Differences in Antibiotic Use Across 576 U.S. Hospitals and 11,701,326 Million Adult Admissions, 2016 – 2017

  21 May 2020

Quantifying the amount and diversity of antibiotic use in United States hospitals assists antibiotic stewardship efforts but is hampered by limited national surveillance. Our study aimed to address this knowledge gap by examining adult antibiotic use across 576 hospitals and nearly 12 million encounters in 2016 – 2017.

Adult inpatient antibiotic use remains high, driven predominantly by broad-spectrum agents. Better understanding reasons for inter-hospital usage differences, including by region and teaching status, may inform efforts to reduce inappropriate antibiotic prescribing.

Author(s): Katherine E Goodman, Sara E Cosgrove, Lisa Pineles, Laurence S Magder, Deverick J Anderson, Elizabeth Dodds Ashley, Ronald E Polk, Hude Quan, William E Trick, Keith F Woeltje, Surbhi Leekha, Anthony D Harris
Effective Surveillance  


Unrestricted financial support by:


Antimicrobial Resistance Fighter Coalition

Bangalore Bioinnovation Centre


EADA 2023

Emerging Antimicrobials and Diagnostics in AMR 2023

International Matchmaking Symposium EADA 2023
Amsterdam, The Netherlands
16/17 November

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