Reducing the use of empiric antibiotic therapy in COVID-19 on hospital admission

  04 June 2021

Empiric antibiotics for community acquired bacterial pneumonia (CABP) are often prescribed to patients with COVID-19, despite a low reported incidence of co-infections. Stewardship interventions targeted at facilitating appropriate antibiotic prescribing for CABP among COVID-19 patients are needed. We developed a guideline for antibiotic initiation and discontinuation for CABP in COVID-19 patients. The purpose of this study was to assess the impact of this intervention on the duration of empiric CABP antibiotic therapy among patients with COVID-19.

Following the implementation of a guideline outlining recommendations for initiating and discontinuing antibiotics for CABP among COVID-19 inpatients, we observed a reduction in antibiotic prescribing and DOT. The guideline also resulted in a significant increase in the rate of guideline-congruent empiric antibiotic initiation.

Further reading: BMC Infectious Diseases
Author(s): Natasha N. Pettit, Cynthia T. Nguyen, Alison K. Lew, Palak H. Bhagat, Allison Nelson, Gregory Olson, Jessica P. Ridgway, Mai T. Pho & Jade Pagkas-Bather
Effective Surveillance  


Unrestricted financial support by:

Antimicrobial Resistance Fighter Coalition


JSS University


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