Prevalence and genomic-based antimicrobial resistance analysis of Avibacterium paragallinarum isolates in Guangdong Province, China

Infectious coryza (IC) is a severe respiratory disease in chickens caused by Avibacterium paragallinarum (A. paragallinarum). A study in Guangdong identified 21 A. paragallinarum isolates, revealing that they ferment glucose but not alginate or galactose. The hmtp210 gene was found to be strongly associated with A. paragallinarum serotypes. The isolates exhibited phenotypic resistance to ampicillin, streptomycin, methotrexate-sulfamethoxazole, and tetracycline, with 14 genes associated with antibiotic resistance. This study contributes to understanding A. paragallinarum antibiotic resistance.