A study today in the Journal of Antimicrobial Chemotherapy reports that nearly 20% of pharmacies in a region of Spain dispense antibiotics without a prescription, especially under patient pressure.
A point prevalence survey conducted at Canadian hospitals shows that national prevalence rates for infection or colonization with antimicrobial-resistant organisms (AROs) saw little change from 2010 to 2016, according to a study today in Infection Control and Hospital Epidemiology.
For decades, doctors have been using antibiotics to fight tuberculosis (TB). And consistently, the microbe responsible for the disease, Mycobacterium tuberculosis, has been fighting back. When confronted with current drugs, such as the antibiotic rifamycin, the bacterium often mutates in ways that make it resistant to the treatment. Rates of rifamycin resistance are steadily rising, which […]
By screening a library of off-patent drugs, scientists have identified a compound with promising broad-spectrum antifungal activity.
California Department of Public Health (CDPH) investigators found that patients with multidrug-resistant tuberculosis (MDR-TB) had effective treatment begun 5 weeks earlier when pyrosequencing (PSQ) was used to detect resistance mutations than when it was not, according to a study yesterday in Clinical Infectious Diseases.
Achieving antimicrobial stewardship programs’ primary goal of using antibiotics responsibly to optimize patient care and minimize development of resistant infections, requires education of and collaboration among multiple parties, including physicians, information technology (IT) specialists, hospital administrators, and patients, according to experts who participated in a Contagion® Peer Exchange panel.
This study determined the frequency of resistance of 135 isolates of Salmonella, including 15 serotypes recovered from chickens purchased from retail outlets (cottage processors and supermarkets) across Trinidad. Resistance to 16 antimicrobial agents was determined by using the disk diffusion method. Resistance among the isolates was related to the type of retail outlet, location of outlets, type […]
Here we combine epidemiological theory and data to assess the potential of POC-RD innovations in a public health context, as a means to limit or even reverse selection for antibiotic resistance.
Since 2010, very few new antibiotics (ceftolozane/tazobactam, ceftazidime/avibactam, meropenem/vaborbactam, plazomicin, eravacycline) have been approved to fight multidrug-resistant Gram-negative bacteria.
Wastewater treatment plants (WWTPs) are thought to be potential incubators of antibiotic resistance. Persistence of commonly used antibiotics in wastewater may increase the potential for selection of resistance genes transferred between bacterial populations, some of which might pose a threat to human health. In this study, we measured the concentrations of ten antibiotics in wastewater […]
Antibiotic resistance is a complex problem in animal husbandry. Antibiotics are essential for both veterinary and human healthcare, but their usage can lead to antimicrobial resistance. Dik Mevius, an expert in the use of antibiotics for livestock management, gives here an overview of this collaborative work and findings within EFFORT where he coordinated the collection of samples and farm data as part of research on antibiotic resistance in the food chain, and zoonotic transmission.
A team of researchers from Massachusetts Institute of Technology has developed a novel approach for eradicating methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa from wounds, using a combination of antibiotics and alginate-encapsulated probiotics. The team’s work appears in the journal Advanced Materials.