Multidrug-resistant Pseudomonas aeruginosa in immunocompromised cancer patients: epidemiology, antimicrobial resistance, and virulence factors

This study examines antimicrobial resistance patterns and virulence properties of Pseudomonas aeruginosa from blood samples of febrile immunocompromised patients. Fifty-two clinical isolates were examined for demographic and clinical characteristics, antimicrobial resistance profiles, and virulence factors. The study found that all isolates exhibited MDR, XDR, and PDR phenotypes, with a crude 30-day mortality rate of 26.9%. The study highlights the escalating load of antimicrobial resistance and significant virulence of P. aeruginosa, affecting available treatment strategies.