Investigating potential transmission of antimicrobial resistance in an open-plan hospital ward: a cross-sectional metagenomic study of resistome dispersion in a lower middle-income setting

  20 March 2021

Antimicrobial resistance (AMR) represents a profound global health threat. Reducing AMR spread requires the identification of transmission pathways. The extent to which hospital wards represent a venue for substantial AMR transmission in low- and middle-income countries settings is poorly understood.

AMR dispersion patterns primarily reflect the placement of particular patients by their condition, rather than AMR transmission. The proportion of AMR determinants that varied with inter-patient distance was limited, suggesting that nosocomial transmission is a relatively minor contributor to population-level carriage.

Author(s): Anushia Ashokan, Josh Hanson, Ne Myo Aung, Mar Mar Kyi, Steven L. Taylor, Jocelyn M. Choo, Erin Flynn, Fredrick Mobegi, Morgyn S. Warner, Steve L. Wesselingh, Mark A. Boyd & Geraint B. Rogers
Effective Surveillance  


Unrestricted financial support by:


Antimicrobial Resistance Fighter Coalition

Bangalore Bioinnovation Centre


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