Faecal microbiota transplantation reduces amounts of antibiotic resistance genes in patients with multidrug-resistant organisms
01 February 2022
Multidrug-resistant organisms (MDROs) such as vancomycin-resistant enterococci (VRE) and carbapenemase-producing Enterobacteriaceae (CPE) are associated with prolonged hospitalisation, increased medical costs, and severe infections. Faecal microbiota transplantation (FMT) has emerged as an important strategy for decolonisation. This study aimed to evaluate the genetic response of MDROs to FMT.
FMT in patients infected with MDROs downregulates the expression of resistance genes, especially VanA, and facilitates MDRO decolonisation.
Further reading: Antimicrobial Resistance and Infection Control
Author(s): JongHoon Hyun, Sang Kil Lee, Jae Hee Cheon, Dong Eun Yong, Hong Koh, Yun Koo Kang, Moo Hyun Kim, Yujin Sohn, Yunsuk Cho, Yae Jee Baek, Jung Ho Kim, Jin Young Ahn, Su Jin Jeong, Joon Sup Yeom & Jun Yong Choi
Healthy Animals
OUR UNDERWRITERS
Unrestricted financial support by:
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LifeArc |
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Antimicrobial Resistance Fighter Coalition |
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Bangalore Bioinnovation Centre |
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INTERNATIONAL FEDERATION PHARMACEUTICAL MANUFACTURERS & ASSOCIATIONS |
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