Emergence and persistent spread of carbapenemase-producing Klebsiella pneumoniae high-risk clones in Greek hospitals, 2013 to 2022
A new highly drug-resistant clone of carbapenemase-producing Klebsiella pneumoniae had been detected in 12 of 15 Greek hospitals participating in a European genomic surveillance project in 2019. We looked at a collection of 10 carbapenem-resistant K. pneumoniae isolates per hospital to see how widely these bacteria had spread in 2022; such timely information could be used for infection prevention and control.
The carbapenemase-producing K. pneumoniae detected in Greek hospitals over a 10-year period mainly belonged to a small number of so-called ‘high-risk clones’ known for their antimicrobial resistance and capacity to spread in healthcare settings. We also noted that new high-risk clones have recently emerged and spread rapidly throughout hospitals in the country.
Infection prevention and control measures need to be enhanced immediately to prevent further spread of highly-drug resistant K. pneumoniae and similar resistant bacteria in hospitals. This study is a model for rapid national molecular surveillance studies that could also be applied in other countries and settings.Effective Surveillance
Join the AMR Insights Ambassador Network today!
Connect to over 650 AMR professionals and students in 65 countries!