Dynamics of extended-spectrum cephalosporin resistance genes in Escherichia coli from Europe and North America

  14 December 2022

Extended-spectrum cephalosporins (ESCs) are critically important antimicrobial agents for human and veterinary medicine. ESC resistance (ESC-R) genes have spread worldwide through plasmids and clonal expansion, yet the distribution and dynamics of ESC-R genes in different ecological compartments are poorly understood. Here we use whole genome sequence data of Enterobacterales isolates of human and animal origin from Europe and North America and identify contrasting temporal dynamics.

Further reading: Nature Communications
Author(s): Roxana Zamudio et al
Effective Surveillance  
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