Comparison of the global prevalence and trend of human intestinal carriage of ESBL-producing Escherichia coli between healthcare and community settings: a systematic review and meta-analysis

  03 June 2022

The widespread intestinal carriage of ESBL-producing Escherichia coli (ESBL E. coli) among both patients and healthy individuals is alarming. However, the global prevalence and trend of this MDR bacterium in healthcare settings remains undetermined. To address this knowledge gap, we performed a comparative meta-analysis of the prevalence in community and healthcare settings.

The global and regional human intestinal ESBL E. coli carriage is increasing in both community and healthcare settings. Carriage rates were generally higher in healthcare than in community settings. Key relevant health organizations should perform surveillance and implement preventive measures to address the spread of ESBL E. coli in both settings.

Author(s): Yihienew M. Bezabih, Alemayehu Bezabih, Michel Dion, Eric Batard, Samson Teka, Abiy Obole, Noah Dessalegn, Alelegn Enyew, Anna Roujeinikova, Endalkachew Alamneh, Corinne Mirkazemi, Gregory M. Peterson, Woldesellassie M. Bezabhe
Effective Surveillance  


Unrestricted financial support by:

Antimicrobial Resistance Fighter Coalition


JSS University

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