Clinical Resistome Screening of 1,110 Escherichia coli Isolates Efficiently Recovers Diagnostically Relevant Antibiotic Resistance Biomarkers and Potential Novel Resistance Mechanisms

  01 September 2019

Multidrug-resistant pathogens represent one of the biggest global healthcare challenges. Molecular diagnostics can guide effective antibiotics therapy but relies on validated, predictive biomarkers. Here the authors present a novel, universally applicable workflow for rapid identification of antimicrobial resistance (AMR) biomarkers from clinical Escherichia coli isolates and quantitatively evaluate the potential to recover causal biomarkers for observed resistance phenotypes.

Further reading: Frontiers in Microbiology
Author(s): Carsten Volz, Jonas Ramoni, Stephan Beisken, Valentina Galata, Andreas Keller, Achim Plum, Andreas E. Posch and Rolf Müller
Effective Surveillance  
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