Characterization of a hemolytic and antibiotic-resistant Pseudomonas aeruginosa strain S3 pathogenic to fish isolated from Mahananda River in India

A virulent strain of Pseudomonas aeruginosa from the Mahananda River showed high hemolytic activity and virulence factors, making it pathogenic to fish. The strain was found to be cytotoxic to the human liver cell line and was similar to P. aeruginosa PAO1. The draft genome sequence contained 5916 coding sequences, eight genes related to hemolysin action, and antibiotic resistance genes like class C and D beta-lactamases, fosA, APH, and catB. This suggests that river water is contaminated with pathogenic P. aeruginosa.