Antimicrobial resistance is a global health crisis and few novel antimicrobials have been discovered in recent decades. Natural products, particularly from Streptomyces, are the source of most antimicrobials, yet discovery campaigns focusing on Streptomyces from the soil largely rediscover known compounds.
UK biotech company Bicycle Therapeutics is to develop a new class of antibacterial agents to tackle antimicrobial resistance (AMR) after receiving a grant of £496,000 ($640,000) from the government
Mechanical engineers from the Korea Advanced Institute of Science and Technology recently developed a microchip antibiotic testing platform that takes only six to seven hours to determine the appropriate medication.
Exponentially increasing amounts of unprocessed bacterial and viral genomic sequence data are stored in the global archives. The ability to query these data for sequence search terms would facilitate both basic research and applications such as real-time genomic epidemiology and surveillance.
Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI) have combined their knowledge of bacterial genetics and web search algorithms to build a DNA search engine for microbial data. The search engine, described in a paper published in Nature Biotechnology, could enable researchers and public health agencies to use genome sequencing data to monitor the spread of antibiotic resistance genes.