First multi-actor partnership tests chemical compounds for antibacterial activity
Antimicrobial resistance (AMR) is a global problem hindering treatment of bacterial infections, rendering many aspects of modern medicine less effective. AMR genes (ARGs) are frequently located on plasmids, which are self-replicating elements of DNA. They are often transmissible between bacteria, and some have spread globally. Novel strategies to combat AMR are needed, and plasmid curing and anti-plasmid approaches could reduce ARG prevalence, and sensitise bacteria to antibiotics.
New research underscores the need to dynamically optimize combination treatments based on the quantitative features of the bacterial response to the antibiotic or the β-lactamase inhibitor.
The Call on Diagnostics and Surveillance 2019 will fund joint transnational research projects addressing the development of diagnostic and surveillance tools, technologies and methods to detect antimicrobial resistance (AMR).
The French government has released €40 million to help fund research into new antibiotics, as antibiotic resistance in France rises up the medical agenda.