The initiative makes Phage Therapy accessible and available to Indian patients suffering from antibiotic-resistant bacterial infections
Special Feature on Antimicrobial Resistance and the Role of Vaccines is dedicated to the memory of microbiologist Stanley Falkow. Professor Falkow was a pioneer in understanding how bacteria cause disease and discovered how antibiotic resistance spreads among bacteria.
Inaccurate drug susceptibility testing by comparison with a reference standard leads to under-treatment of drug-resistant tuberculosis and increased mortality. Rapid molecular drug susceptibility test of first-line and second-line drugs at diagnosis is required to improve outcomes in patients with MDR tuberculosis and pre-XDR or XDR tuberculosis.
Effective use of microbiology test results may positively influence patient outcomes and limit the use of broad-spectrum antibiotics. However, studies indicate that their potential is not fully utilized.
A risk-based approach in empiric sepsis therapy has the potential to better target the use of reserve antimicrobial agents aimed at multi-resistant Gram-negative pathogens.