Global burden of latent multidrug-resistant tuberculosis: trends and estimates based on mathematical modelling

  09 July 2019

To end the global tuberculosis epidemic, latent tuberculosis infection needs to be addressed. All standard treatments for latent tuberculosis contain drugs to which multidrug-resistant (MDR) Mycobacterium tuberculosis is resistant. We aimed to estimate the global burden of multidrug-resistant latent tuberculosis infection to inform tuberculosis elimination policy.

The authors estimate that three in every 1000 people globally carry latent MDR tuberculosis infection, and prevalence is around ten times higher among those younger than 15 years. If current trends continue, the proportion of latent tuberculosis caused by MDR strains will increase, which will pose serious challenges for management of latent tuberculosis—a cornerstone of tuberculosis elimination strategies.

Authors: Gwenan M Knight, C Finn McQuaid, Peter J Dodd, Rein M G J Houben
Effective surveillance  
Back


Emerging Antimicrobials and Diagnostics in AMR 2019

International Matchmaking Symposium on 19-20 November, 2019 in Amsterdam, The Netherlands.

More information
What is going on with AMR?
Stay tuned with remarkable global AMR news and developments!